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Description: ERDS is an open-source software free to academia and nor-profit organization, designed for inferring copy number variants CNVs in high-coverage human genomes using next generation sequence NGS data. Dans cet exemple, je vous propose de tlcharger le logiciel Picasa tutorial-gratuit. Le code du coupon n'est valable que jusqu'au 31 juillet Net , PCWinSoft , Screen Capture , stream , audio tracks , settings , quality , date , tracks , browsers , shapes , text stamps , drawings , media servers , time stamps , polygons , animated text strings , live cameras. The LLVM Core libraries are well documented, and it is particularly easy to invent your own language or port an existing compiler to use LLVM as an optimizer and code generator.

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Outside France, the built-in map is still available. How to clean registry En avant. Signaler Commenter la réponse de madmyke. Très simple à manipuler, le logiciel est gratuit pour un usage privé. Significant increase of the level of details:. Most GPS devices support enabling and disabling maps, so you can easily switch between different maps.

This product does not include a cable for data exchange with a PC. The topographic map of France is available in five different versions: Signaler Commenter la réponse de Utilisateur anonyme.

Now you can plan and organize trips with MapSource, a very useful computer software. For a detailed description click on the area in the image above. Signaler Commenter la réponse de mauriceweb. Fracne votre question Signaler. Très simple à manipuler, mapsourcee logiciel est gratuit pour un usage privé. Téléchargez gratuitement Ma;source MapSource 6. Signaler Commenter la réponse de Utilisateur anonyme. Coverage — Features — Prices — Examples — Order. The maps of these products support the autorouting feature of the GPS models which are capable of computing routes.

Significant increase of the level of details: Garkin table of contents Features: If you need such a connection cable, see our selection of options. If you insert the memory card into a GPS device, its functionality will be enhanced as follows: Mapsuorce there is a built-in map, then the map of France will overlay the built-in map.

Autorouting on a PC: Specifications and packaging of the products garmln subject to change without notice. If you connect the GPS with a computer or if you insert ampsource memory card in a computer where BaseCamp is installed, you can use the following features: Now you can plan and organize trips with MapSource, a very useful computer software. Mappsource la réponse de Utilisateur anonyme. If you insert the memory card into a GPS device, its functionality will be enhanced as follows:.

Description: CD-HIT is a very widely used program for clustering and comparing protein or nucleotide sequences. Description: Cell Ranger is a set of analysis pipelines that process Chromium single cell 3-RNA-seq output to align reads, generate gene-cell matrices and perform clustering and gene expression analysis.

Cell Ranger 1. Cell Ranger includes four main gene expression pipelines: - cellranger mkfastq wraps Illumina's bcl2fastq to correctly demultiplex Chromium-prepared sequencing samples and to convert barcode and read data to FASTQ files.

Description: [Centrifuge] is a novel microbial classification engine that enables rapid, accurate and sensitive labeling of reads and quantification of species on desktop computers.

The system uses a novel indexing scheme based on the Burrows-Wheeler transform BWT and the Ferragina-Manzini FM index, optimized specifically for the metagenomic classification problem. Centrifuge requires a relatively small index 4. Description: The Community Earth System Model CESM is a fully-coupled, global climate model that provides state-of-the-art computer simulations of the Earth's past, present, and future climate states. Description: CFOUR Coupled-Cluster techniques for Computational Chemistry is a program package for performing high-level quantum chemical calculations on atoms and molecules.

The major strength of the program suite is its rather sophisticated arsenal of high-level ab initio methods for the calculation of atomic and molecular properties. Virtually all approaches based on Muller-Plesset MP perturbation theory and the coupled-cluster approximation CC are available; most of these have complementary analytic derivative approaches within the package as well.

CFOUR is not a commercial code. It is rather a program that is undergoing development; new techniques and improvements are constantly being made mainly in the groups of John F. For non-commercial purposes there is no charge to obtain CFOUR; one must simply sign a license agreement. Description: The CGNS system is designed to facilitate the exchange of data between sites and applications, and to help stabilize the archiving of aerodynamic data. Description: CheMPS2 is a scientific library which contains a spin-adapted implementation of the density matrix renormalization group DMRG for ab initio quantum chemistry.

Description: Circos is a software package for visualizing data and information. It visualizes data in a circular layout - this makes Circos ideal for exploring relationships between objects or positions. There are other reasons why a circular layout is advantageous, not the least being the fact that it is attractive. Circos is ideal for creating publication-quality infographics and illustrations with a high data-to-ink ratio, richly layered data and pleasant symmetries.


You have fine control each element in the figure to tailor its focus points and detail to your audience. Description: The CLHEP project is intended to be a set of HEP-specific foundation and utility classes such as random generators, physics vectors, geometry and linear algebra. CLHEP is structured in a set of packages independent of any external package.

Description: Clustal Omega is a multiple sequence alignment program for proteins. It produces biologically meaningful multiple sequence alignments of divergent sequences. Description: CMake, the cross-platform, open-source build system. CMake is a family of tools designed to build, test and package software.

Description: The Combinatorial BLAS CombBLAS is an extensible distributed-memory parallel graph library offering a small but powerful set of linear algebra primitives specifically targeting graph analytics. Description: COMSOL Multiphysics is a general-purpose software platform, based on advanced numerical methods, for modeling and simulating physics-based problems. Description: Corset is a command-line software program to go from a de novo transcriptome assembly to gene-level counts.

Our software takes a set of reads that have been multi-mapped to the transcriptome where multiple alignments per read were reported and hierarchically clusters the transcripts based on the proportion of shared reads and expression patterns.

It will report the clusters and gene-level counts for each sample, which are easily tested for differential expression with count based tools such as edgeR and DESeq. Description: CP2K is a freely available GPL program, written in Fortran 95, to perform atomistic and molecular simulations of solid state, liquid, molecular and biological systems. It provides a general framework for different methods such as e. Description: Scientific workflow engine designed for simplicity and scalability.

In the context of the CSlib, it can used to couple two scientific applications apps together where one app acts as the client and the other as the server. The client sends messages to the server requesting it perform specific computations and return the results.

Description: CST offers accurate, efficient computational solutions for electromagnetic design and analysis. CST simulation is user-friendly and enables users to choose the most appropriate method for the design and optimization of devices operating in a wide range of frequencies.

Please note that we installed only Graphic frontend and command line interface. You need to provide your own license server in order to be able to run CST.

Description: Automated testing framework for C. Description: A genomic linkage feature visualization tools based on Perl. Description: Seismic Unix is a seismic processing and research environment developed at the Center for Wave Phenomena. Description: The Dakota project delivers both state-of-the-art research and robust, usable software for optimization and UQ.

Broadly, the Dakota software's advanced parametric analyses enable design exploration, model calibration, risk analysis, and quantification of margins and uncertainty with computational models.

These capabilities may be used on their own or as components within advanced strategies such as hybrid optimization, surrogate-based optimization, mixed integer nonlinear programming, or optimization under uncertainty.

Any published work arising from use of one of the Dalton programs must acknowledge that by a proper reference. The following list of capabilities of the Dalton programs should give you some indication of whether or not the Dalton suite is able to meet your requirements.. Description: DAMASK is a flexible and hierarchically structured model of material point behavior for the solution of elastoplastic boundary value problems along with damage and thermal physics.

Description: Delly is an integrated structural variant SV prediction method that can discover, genotype and visualize deletions, tandem duplications, inversions and translocations at single-nucleotide resolution in short-read massively parallel sequencing data. Both packages are mainly intended to be used to evaluate de novo transcriptome assemblies, although REF-EVAL can be used to compare sets of any kinds of genomic sequences.

Description: DiscoSnp is designed for discovering all kinds of SNPs not only isolated ones , as well as insertions and deletions, from raw set s of reads. The number of input read sets is not constrained, it can be one, two, or more.

No reference genome is needed. Todorov and W. Description: The debug memory allocation or dmalloc library has been designed as a drop in replacement for the system s malloc, realloc, calloc, free and other memory management routines while providing powerful debugging facilities configurable at runtime.

It also provides support for the debugging of threaded programs. The package includes the library, configuration scripts, debug utility application, test program, and documentation. NET is a free, cross-platform, open source developer platform for building many different types of applications. NET, you can use multiple languages, editors, and libraries to build for web, mobile, desktop, gaming, and IoT.

Contains the SDK and the Runtime. Description: This repository contains an implementation of the EEMS method for analyzing and visualizing spatial population structure from geo-referenced genetic samples. EEMS uses the concept of effective migration to model the relationship between genetics and geography, and it outputs an estimated effective migration surface hence, EEMS - a visual representation of population structure that can highlight potential regions of higher-than-average and lower-than-average historic gene flow.

Description: Elixir is a dynamic, functional language designed for building scalable and maintainable applications. Description: ELSI: ELectronic Structure Infrastructure is a software bundle and unified interface for methods that solve or circumvent eigenvalue problems in the self-consistent field cycle of density-functional theory.

EMBnet user community. Description: ERDS is an open-source software free to academia and nor-profit organization, designed for inferring copy number variants CNVs in high-coverage human genomes using next generation sequence NGS data. When a CNV presents in a test genome, multiple signatures, weak or strong, would present in the alignment data. Description: Erlang is a general-purpose concurrent, garbage-collected programming language and runtime system.

Description: Exonerate is a generic tool for pairwise sequence comparison. It allows you to align sequences using a many alignment models, using either exhaustive dynamic programming, or a variety of heuristics. Description: Faiss is a library for efficient similarity search and clustering of dense vectors. It contains algorithms that search in sets of vectors of any size, up to ones that possibly do not fit in RAM.

It also contains supporting code for evaluation and parameter tuning. Some of the most useful algorithms are implemented on the GPU. ANI is defined as mean nucleotide identity of orthologous gene pairs shared between two microbial genomes. FastANI supports pairwise comparison of both complete and draft genome assemblies.

Description: FastME: a comprehensive, accurate and fast distance-based phylogeny inference program.

Description: A tool designed to provide fast all-in-one preprocessing for FastQ files. Description: FastQ Screen allows you to screen a library of sequences in FastQ format against a set of sequence databases so you can see if the composition of the library matches with what you expect. Description: FastQC is a quality control application for high throughput sequence data. It reads in sequence data in a variety of formats and can either provide an interactive application to review the results of several different QC checks, or create an HTML based report which can be integrated into a pipeline.

Description: While preserving all the simulation flexibility of simcoal2, fastsimcoal is now implemented under a faster continous-time sequential Markovian coalescent approximation, allowing it to efficiently generate genetic diversity for different types of markers along large genomic regions, for both present or ancient samples. It includes a parameter sampler allowing its integration into Bayesian or likelihood parameter estimation procedure. The time of sampling can be specified independently for each sample, allowing for serial sampling in the same or in different populations.

Description: FastTree infers approximately-maximum-likelihood phylogenetic trees from alignments of nucleotide or protein sequences. FastTree can handle alignments with up to a million of sequences in a reasonable amount of time and memory. Description: FEKO is a comprehensive computational electromagnetics CEM code used widely in the telecommunications, automobile, space and defense industries. Description: FFTW is a C subroutine library for computing the discrete Fourier transform DFT in one or more dimensions, of arbitrary input size, and of both real and complex data.

Description: Filtlong is a tool for filtering long reads by quality. It can take a set of long reads and produce a smaller, better subset. Description: Flexbar flexible barcode and adapter removal: The program Flexbar preprocesses high-throughput sequencing data efficiently.

It demultiplexes barcoded runs and removes adapter sequences. Several adapter removal presets for Illumina libraries are included. Flexbar computes exact overlap alignments using SIMD and multicore parallelism. Moreover, trimming and filtering features are provided, e. Flexbar increases read mapping rates and improves genome as well as transcriptome assemblies.

Unique molecular identifiers can be extracted in a flexible way. The software supports data in fasta and fastq format from multiple sequencing platforms. Description: ANSYS Fluent software contains the broad physical modeling capabilities needed to model flow, turbulence, heat transfer, and reactions for industrial applications, ranging from air flow over an aircraft wing to combustion in a furnace, from bubble columns to oil platforms, from blood flow to semiconductor manufacturing, and from clean room design to wastewater treatment plants.

Fluent covers a broad reach, including special models with capabilities to model in-cylinder combustion, aero-acoustics, turbomachinery and multiphase systems.

Description: fmt formerly cppformat is an open-source formatting library. Description: FragGeneScan is an application for finding fragmented genes in short reads. Description: Frealign is a program for high-resolution refinement of 3D reconstructions from cryo-EM images of single particles. Description: Bayesian haplotype-based polymorphism discovery and genotyping. Description: FreeSurfer is a set of tools for analysis and visualization of structural and functional brain imaging data.

FreeSurfer contains a fully automatic structural imaging stream for processing cross sectional and longitudinal data.

Description: FreeXL is an open source library to extract valid data from within an Excel. It provides primitives for one-sided communication Get, Put, Accumulate and Atomic Operations read increment. It supports blocking and non-blocking primtives, and supports location consistency. I8 version. It includes experimental MU CoupledCluster theory code. The toolkit offers a wide variety of tools, with a primary focus on variant discovery and genotyping as well as strong emphasis on data quality assurance.

Its robust architecture, powerful processing engine and high-performance computing features make it capable of taking on projects of any size. Description: GCTA Genome-wide Complex Trait Analysis was originally designed to estimate the proportion of phenotypic variance explained by all genome-wide SNPs for complex traits the GREML method , and has subsequently extended for many other analyses to better understand the genetic architecture of complex traits.

GCTA currently supports the following analyses. As a library, it presents a single abstract data model to the calling application for all supported formats. It also comes with a variety of useful commandline utilities for data translation and processing. Description: Geant4 is a toolkit for the simulation of the passage of particles through matter. Its areas of application include high energy, nuclear and accelerator physics, as well as studies in medical and space science.

Description: The GenomeTools genome analysis system is a free collection of bioinformatics tools in the realm of genome informatics combined into a single binary named gt. It is based on a C library named libgenometools which contains a wide variety of classes for efficient and convenient implementation of sequence and annotation processing software. Description: Ghostscript is a versatile processor for PostScript data with the ability to render PostScript to different targets.

It used to be part of the cups printing stack, but is no longer used for that. Description: git-annex allows managing files with git, without checking the file contents into git. While that may seem paradoxical, it is useful when dealing with files larger than git can currently easily handle, whether due to limitations in memory, time, or disk space.

Although the gene finder conforms to the overall mathematical framework of a GHMM, additionally it incorporates splice site models adapted from the GeneSplicer program and a decision tree adapted from GlimmerM. It also utilizes Interpolated Markov Models for the coding and noncoding models. Description: GMP is a free library for arbitrary precision arithmetic, operating on signed integers, rational numbers, and floating point numbers.

Homepage: none Prerequisites: - Description:. Description: Gmsh is a 3D finite element grid generator with a build-in CAD engine and post-processor. Description: GMT is an open source collection of about 80 command-line tools for manipulating geographic and Cartesian data sets including filtering, trend fitting, gridding, projecting, etc.

Description: Go is an open source programming language that makes it easy to build simple, reliable, and efficient software. Please see the project page for more information as well as the mailing list for questions, discussions, and development. See the separate Google Mock documentation. Description: Grackle is a chemistry and radiative cooling library for astrophysical simulations and models. GRASS is currently used in academic and commercial settings around the world, as well as by many governmental agencies and environmental consulting companies.

A useful set of command line tools is also provided to give quick access to GRIB messages. The library provides a wide range of mathematical routines such as random number generators, special functions and least-squares fitting.

It is an Open Source Free Software Library intended to provide a set of useful functions to deal with 3D surfaces meshed with interconnected triangles. Description: The Gurobi Optimizer is a state-of-the-art solver for mathematical programming. The solvers in the Gurobi Optimizer were designed from the ground up to exploit modern architectures and multi-core processors, using the most advanced implementations of the latest algorithms.

Description: Harminv is a free program and accompanying library to solve the problem of harmonic inversion - given a discrete-time, finite-length signal that consists of a sum of finitely-many sinusoids possibly exponentially decaying in a given bandwidth, it determines the frequencies, decay constants, amplitudes, and phases of those sinusoids. Description: HDF also known as HDF4 is a library and multi-object file format for storing and managing data between machines.

Description: HDF5 is a data model, library, and file format for storing and managing data. Description: HDF5 is a unique technology suite that makes possible the management of extremely large and complex data collections. Description: The HH-suite is an open-source software package for sensitive protein sequence searching based on the pairwise alignment of hidden Markov models HMMs.

Description: HISAT2 is a fast and sensitive alignment program for mapping next-generation sequencing reads both DNA and RNA against the general human population as well as against a single reference genome. Description: HMMER is used for searching sequence databases for homologs of protein sequences, and for making protein sequence alignments.

It implements methods using probabilistic models called profile hidden Markov models profile HMMs. Description: HPL is a software package that solves a random dense linear system in double precision 64 bits arithmetic on distributed-memory computers.

It can thus be regarded as a portable as well as freely available implementation of the High Performance Computing Linpack Benchmark. Description: HyPhy: Hypothesis testing using Phylogenies.

HyPhy is an open-source software package for the analysis of genetic sequences using techniques in phylogenetics, molecular evolution, and machine learning. It features a complete graphical user interface GUI and a rich scripting language for limitless customization of analyses. Additionally, HyPhy features support for parallel computing environments via message passing interface MPI and it can be compiled as a shared library and called from other programming environments such as Python and R.

Description: Hypre is a library for solving large, sparse linear systems of equations on massively parallel computers. The problems of interest arise in the simulation codes being developed at LLNL and elsewhere to study physical phenomena in the defense, environmental, energy, and biological sciences. Description: Ichthyop is a free Java tool designed to study the effects of physical and biological factors on ichthyoplankton dynamics.

It incorporates the most important processes involved in fish early life: spawning, movement, growth, mortality and recruitment. It is an extension of IDBA algorithm. In each iteration, short and low-depth contigs are removed iteratively with cutoff threshold from low to high to reduce the errors in low-depth and high-depth regions. Paired-end reads are aligned to contigs and assembled locally to generate some missing k-mers in low-depth regions.

With these technologies, IDBA-UD can iterate k value of de Bruijn graph to a very large value with less gaps and less branches to form long contigs in both low-depth and high-depth regions. Description: igraph is a collection of network analysis tools with the emphasis on efficiency, portability and ease of use.

Description: Intel Math Kernel Library is a library of highly optimized, extensively threaded math routines for science, engineering, and financial applications that require maximum performance. Note: like Open MPI , this module's mpicc calls the toolchain compiler. Description: InterProScan is a sequence analysis application nucleotide and protein sequences that combines different protein signature recognition methods into one resource.

Description: Intel Integrated Performance Primitives Intel IPP is an extensive library of multicore-ready, highly optimized software functions for multimedia, data processing, and communications applications. Intel IPP offers thousands of optimized functions covering frequently used fundamental algorithms.


Description: IPython kernelspec for Python 2. Description: IPython kernelspec for Python 3.

Logiciels disponibles

Description: The Intel Trace Collector is a low-overhead tracing library that performs event-based tracing in applications. The Intel Trace Analyzer provides a convenient way to monitor application activities gathered by the Intel Trace Collector through graphical displays.

Description: Insight Segmentation and Registration Toolkit ITK provides an extensive suite of software tools for registering and segmenting multidimensional imaging data. Description: The JasPer Project is an open-source initiative to provide a free software-based reference implementation of the codec specified in the JPEG Part-1 standard.

It is distributed under the GPL license version 3 or higher and publications resulting from its use must cite: R. Sundararaman, K. Letchworth-Weaver, K. Schwarz, D. Gunceler, Y. Ozhabes and T. Description: Jellyfish is a tool for fast, memory-efficient counting of k-mers in DNA. Description: A high-level, high-performance dynamic language for technical computing. Description: kallisto is a program for quantifying abundances of transcripts from RNA-Seq data, or more generally of target sequences using high-throughput sequencing reads.

Description: OpenKIM is an online suite of open source tools for molecular simulation of materials. These tools help to make molecular simulation more accessible and more reliable. Within OpenKIM, you will find an online resource for standardized testing and long-term warehousing of interatomic models and data, and an application programming interface API standard for coupling atomistic simulation codes and interatomic potential subroutines.

For that purpose it provides abstractions for both parallel execution of code and data management. Kokkos is designed to target complex node architectures with N-level memory hierarchies and multiple types of execution resources.

Description: Kraken is a system for assigning taxonomic labels to short DNA sequences, usually obtained through metagenomic studies. Previous attempts by other bioinformatics software to accomplish this task have often used sequence alignment or machine learning techniques that were quite slow, leading to the development of less sensitive but much faster abundance estimation programs.

Kraken aims to achieve high sensitivity and high speed by utilizing exact alignments of k-mers and a novel classification algorithm. LAMMPS has potentials for solid-state materials metals, semiconductors and soft matter biomolecules, polymers and coarse-grained or mesoscopic systems. It can be used to model atoms or, more generically, as a parallel particle simulator at the atomic, meso, or continuum scale.

It can be coupled to various programs. Description: LAST finds similar regions between sequences. Description: Open source density functional tight binding molecular dynamics. Description: LevelDB is a fast key-value storage library written at Google that provides an ordered mapping from string keys to string values. Description: libcerf is a self-contained numeric library that provides an efficient and accurate implementation of complex error functions, along with Dawson, Faddeeva, and Voigt functions.

Description: libctl is a free Guile-based library implementing flexible control files for scientific simulations. Description: The libevent API provides a mechanism to execute a callback function when a specific event occurs on a file descriptor or after a timeout has been reached.


Furthermore, libevent also support callbacks due to signals or regular timeouts. Description: GD is an open source code library for the dynamic creation of images by programmers. Description: A library to compute the exchange and correlation energy and potential in spherical i. It is based on SiestaXC. Description: Libint library is used to evaluate the traditional electron repulsion and certain novel two-body matrix elements integrals over Cartesian Gaussian functions used in modern atomic and molecular theory.

Description: GNU libmatheval is a library callable from C and Fortran to parse and evaluate symbolic expressions input as text. Description: libmaus2 is a collection of data structures and algorithms. Description: The libMesh library provides a framework for the numerical simulation of partial differential equations using arbitrary unstructured discretizations on serial and parallel platforms.

A major goal of the library is to provide support for adaptive mesh refinement AMR computations in parallel while allowing a research scientist to focus on the physics they are modeling.

It implements the orbital minimization method OMM , which works within a density matrix formalism. Description: Sodium is a modern, easy-to-use software library for encryption, decryption, signatures, password hashing and more. Description: Library implementing tricubic interpolation.

Description: Libxc is a library of exchange-correlation functionals for density-functional theory. The aim is to provide a portable, well tested and reliable set of exchange and correlation functionals.

Description: C library for computing moments of the product of an exponential-family likelihood with a Normal distribution. Description: Lis, a Library of Iterative Solvers for linear systems, is a parallel library for solving linear equations and eigenvalue problems that arise in the numerical solution of partial differential equations using iterative methods. The installation of Lis requires a C compiler.

The Fortran interface requires a Fortran compiler, and the algebraic multigrid preconditioner requires a Fortran 90 compiler. Both the Harwell-Boeing and Matrix Market formats are supported to import and export user data. Description: The LLVM Core libraries provide a modern source- and target-independent optimizer, along with code generation support for many popular CPUs as well as some less common ones!

The LLVM Core libraries are well documented, and it is particularly easy to invent your own language or port an existing compiler to use LLVM as an optimizer and code generator. Description: LMDB is a fast, memory-efficient database. With memory-mapped files, it has the read performance of a pure in-memory database while retaining the persistence of standard disk-based databases. Description: A probabilistic framework for structural variant discovery. Description: MACH 1. Description: make Description: Manta calls structural variants SVs and indels from mapped paired-end sequencing reads.

Manta discovers, assembles and scores large-scale SVs, medium-sized indels and large insertions within a single efficient workflow. Manta combines paired and split-read evidence during SV discovery and scoring to improve accuracy, but does not require split-reads or successful breakpoint assemblies to report a variant in cases where there is strong evidence otherwise. There is experimental support for analysis of unmatched tumor samples as well. See the user guide for a full description of capabilities and limitations.

Description: MARVEL consists of a set of tools that facilitate the overlapping, patching, correction and assembly of noisy not so noisy ones as well long reads. MaSuRCA can assemble data sets containing only short reads from Illumina sequencing or a mixture of short reads and long reads Sanger, , Pacbio and Nanopore. Description: Binary maven install, Apache Maven is a software project management and comprehension tool. Based on the concept of a project object model POM , Maven can manage a project's build, reporting and documentation from a central piece of information.

Description: The MCL algorithm is short for the Markov Cluster Algorithm, a fast and scalable unsupervised cluster algorithm for networks also known as graphs based on simulation of stochastic flow in graphs. MCL has been applied in a number of different domains, mostly in bioinformatics. It makes use of succinct de Bruijn graph SdBG to achieve low memory assembly.

Description: Distributed and scalable assembler for eukaryotic genomes. Meraculous is a whole genome assembler for Next Generation Sequencing data geared for large genomes. Meraculous achieves high performance with large datasets by utilizing lightweight data structures and multi-threaded parallelization, allowing to assemble human-sized genomes on commodity clusters in under a day.


The process pipeline implements a highly transparent and portable model of job control and monitoring where different assembly stages can be executed and re-executed separately or in unison on a wide variety of architectures.

Description: Mesa is an open-source implementation of the OpenGL specification - a system for rendering interactive 3D graphics. Description: Model Evaluation Tools MET is a highly configurable, state-of-the-art suite of verification tools designed for the verification and evaluation of numerical weather forecasts. Description: METAL provides a computationally efficient tool for meta-analysis of genome-wide association scans, which is a commonly used approach for improving power complex traits gene mapping studies.

METAL provides a rich scripting interface and implements efficient memory management to allow analyses of very large data sets and to support a variety of input file formats. Description: MetaPhlAn is a computational tool for profiling the composition of microbial communities Bacteria, Archaea, Eukaryotes and Viruses from metagenomic shotgun sequencing data with species level resolution. Description: METIS is a set of serial programs for partitioning graphs, partitioning finite element meshes, and producing fill reducing orderings for sparse matrices.

The algorithms implemented in METIS are based on the multilevel recursive-bisection, multilevel k-way, and multi-constraint partitioning schemes. Description: Ultrafast de novo assembly for long noisy reads though having no consensus step. Description: minimac2 is an improved version of Minimac. It is designed to work on phased genotypes and can handle very large reference panels with hundreds or thousands of haplotypes.

The name has two parts. The first, mini, refers to the modest amount of computational resources it requires. The second, mac, is short hand for MaCH, our widely used algorithm for genotype imputation. Description: Minimac3 is a lower memory and more computationally efficient implementation of the genotype imputation algorithms in minimac and minimac2. Minimac3 is designed to handle very large reference panels in a more computationally efficient way with no loss of accuracy.

Description: Minimap2 is a fast sequence mapping and alignment program that can find overlaps between long noisy reads, or map long reads or their assemblies to a reference genome optionally with detailed alignment i. On limited test data sets, minimap2 is over 20 times faster than most other long-read aligners. Kindly cite the arti cle if you are using MITObim in your work.

Description: MiXCR is a universal framework that processes big immunome data from raw sequences to quantitated clonotypes. MiXCR efficiently handles paired- and single-end reads, considers sequence quality, corrects PCR errors and identifies germline hypermutations. The software supports both partial- and full-length profiling and employs all available RNA or DNA information, including sequences upstream of V and downstream of J gene segments.

Description: An open source, cross-platform, implementation of C and the CLR that is binary compatible with Microsoft.


Description: Mothur is a single piece of open-source, expandable software to fill the bioinformatics needs of the microbial ecology community. The package provides users with a number of useful tools for their MPI programs. The latest version is called MPE2. Current available tools under MPE2 are the following: 1. A set of profiling libraries to collect information about the behavior of MPI programs. Linking the user MPI program with the libraries will generate logfile for postmortem visualization when the user program is executed.

An MPI collective and datatype checking library. A shared-display parallel X graphics library. A profiling wrapper generator for MPI interface. Routines for sequentializing a section of code being executed in parallel. Debugger setup routines. Description: MrBayes is a program for the Bayesian estimation of phylogeny. Description: MRtrix provides a set of tools to perform diffusion-weighted MR white-matter tractography in a manner robust to crossing fibres, using constrained spherical deconvolution CSD and probabilistic streamlines.

This project serves as the workhorse implementation of the method used as a standard force-matching code. The development of MS-CG is supported by academic research grants. If you use this package, please cite at least one of these papers: - S.

Izvekov and G. Voth, J. Noid, et al. Noid et al. Lu, S. Izvekov, A. Das, H. Andersen, and G. Voth, Journal of Chemical Theory and Computation, 6 3 , In short, msmc can infer the scaled population size of a single population as a function of time the timing and nature of population separations between two populations from multiple phased haplotypes.

Description: A multifunctional wavefunction analyzer. In addition to the N-fold overlaps you can detect solitary regions which are the input regions that do not overlap with any other region in the input data set, and union overlaps that is the union of the input regions that overlap at least once somewhere. Description: MUMmer is a system for rapidly aligning entire genomes, whether in complete or draft form. AMOS makes use of it. It works by transforming a mathematical expression into bytecode and precalculating constant parts of the expression.

Most users learn everything they need to know about MUSCLE in a few minutes-only a handful of command-line options are needed to perform common alignment tasks. Description: NAMD is a parallel molecular dynamics code designed for high-performance simulation of large biomolecular systems. Description: Software package for signal-level analysis of Oxford Nanopore sequencing data.

Nanopolish can calculate an improved consensus sequence for a draft genome assembly, detect base modifications, call SNPs and indels with respect to a reference genome and more. Description: NCL is an interpreted language designed specifically for scientific data analysis and visualization. Description: Ncview is a visual browser for netCDF format files.

Typically you would use ncview to get a quick and easy, push-button look at your netCDF files. You can view simple movies of the data, view along various dimensions, take a look at the actual data values, change color maps, invert the data, etc. Description: Neper is a software package for polycrystal generation and meshing. It can deal with 2D and 3D polycrystals with very large numbers of grains. Description: NetCDF network Common Data Form is a set of software libraries and machine-independent data formats that support the creation, access, and sharing of array-oriented scientific data.

Description: NetworkX is a Python package for the creation, manipulation, and study of the structure, dynamics, and functions of complex networks. Emphasis is on the kind of operations needed in statistical calculations such as least squares, linear equation solve and eigenvalues. Description: ngsTools is a collection of programs for population genetics analyses from NGS data, taking into account data statistical uncertainty.

The methods implemented in these programs do not rely on SNP or genotype calling, and are particularly suitable for low sequencing depth data. An application note illustrating its application has published Fumagalli et al.

Description: Ninja is a small build system with a focus on speed. Description: Node. Description: Network Security Services NSS is a set of libraries designed to support cross-platform development of security-enabled client and server applications.

Description: NTPoly is a massively parallel library for computing the functions of sparse, symmetric matrices based on polynomial expansions. Description: NWChem aims to provide its users with computational chemistry tools that are scalable both in their ability to treat large scientific computational chemistry problems efficiently, and in their use of available parallel computing resources from high-performance parallel supercomputers to conventional workstation clusters.

NWChem software can handle: biomolecules, nanostructures, and solid-state; from quantum to classical, and all combinations; Gaussian basis functions or plane-waves; scaling from one to thousands of processors; properties and relativity. Description: GNU Octave is a high-level interpreted language, primarily intended for numerical computations.

Description: Octopus is a scientific program aimed at the ab initio virtual experimentation on a hopefully ever-increasing range of system types. Nuclei are described classically as point particles. Electron-nucleus interaction is described within the pseudopotential approximation. Description: Open Babel is a chemical toolbox designed to speak the many languages of chemical data. It's an open, collaborative project allowing anyone to search, convert, analyze, or store data from molecular modeling, chemistry, solid-state materials, biochemistry, or related areas.

Description: OpenColorIO OCIO is a complete color management solution geared towards motion picture production with an emphasis on visual effects and computer animation.

OpenCV was built to provide a common infrastructure for computer vision applications and to accelerate the use of machine perception in the commercial products. OpenFOAM has an extensive range of features to solve anything from complex fluid flows involving chemical reactions, turbulence and heat transfer, to solid dynamics and electromagnetics. Description: OpenImageIO is a library for reading and writing images, and a bunch of related classes, utilities, and applications. Description: OpenMM is a toolkit for molecular simulation.